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Cyclobenzaprine is a skeletal muscle relaxant and a central nervous system (CNS) depressant. It is marketed as Flexeril (5 and 10 mg tablets). Both the 5 and 10 milligram tablets are available generically. The exact mechanism of action for cyclobenzaprine is unknown. Current research appears to indicate that cyclobenzaprine acts on the locus coeruleus where it results in increased norepinephrine release, potentially through the gamma fibers, which innervate and inhibit the alpha motor neurons in the ventral horn of the spinal cord.

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